When, Sakyamuni Buddha, the founder of Buddhism, was living and teaching many were jealous of his name and fame. Among them were six demon kings including Dut Garab Wangchuk, the principle demon. Out of their burning jealousy, they desired to harm and hurt Buddha. So, they looked for ways, but failed to find one.
Since they found no way to hurt Buddha, they wished him the worst. They hoped, wished and prayed intensely for the worst thing to happen for Buddha
Then one day, an evil Ogress dripped drops of her menstrual drop and from there grew saplings that blossomed into plant. Being evil herself, the plant that grew from her blood was evil energy of the evil wishes of the Demon Kings. And that plant is what we call tobacco today.
Tobacco – the guide that leads the blind on a false path which ends in a precipice
by Kyabjé Jigdrèl Yeshé Dorje, Düd’jom Rinpoche